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Choose “Load plugin from file” at lower right, then navigate to where you saved that zip file. Click on the gears-meshing “Preferences” icon at the top right of the screen, then click on the green puzzle piece “Plugins” at the bottom of this window.
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To install it, download the zip file from the Mobileread forum post, then launch Calibre. The plugin uses Windows’s built-in text-to-speech system so only works on Windows, and is pretty primitive thus far - the programmer said he just wrote it over a weekend and called it a “very rough alpha.” Still, it shows some promise. A programmer on Mobileread has come out with a new Calibre plugin that will enable text-to-speech from Calibre’s book viewer software.
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